Nathanael R. Fillmore
People / Jennifer La
JL
Collaborator

Jennifer La

VA Boston Healthcare System / Harvard Medical School

63 shared works · collaborating since 2020

Shared publications

2026

Association of Frailty With Transfusions, Hospitalizations, and Survival in Patients With Myelodysplastic Syndrome Initiating Hypomethylating Agents.

Anahid Hamparsumian†, Jennifer La†, Mayuri Dharne, Gary Gilbert, Mary T. Brophy, Nhan V. Do, Dae Hyun Kim, Jane A. Driver, Nathanael R. Fillmore‡, Clark DuMontier‡† Equal first authorship · ‡ Equal senior authorship

EJHaem7(4), e70352
U.S. Veterans and VA Data Retrospective Cohort Study Frailty Overall Survival Hospitalization Metrics
2026

Development and validation of venous thromboembolism-bidirectional encoder representations from transformers (VTE-BERT) natural language processing model.

Omid Jafari, Shengling Ma, Barbara D. Lam, Jun Y. Jiang, Emily Zhou, Mrinal Ranjan, Justine Ryu, Raka Bandyo, Arash Maghsoudi, Bo Peng, Christopher I. Amos, Abiodun Oluyomi, Nathanael R. Fillmore, Jennifer La‡, Ang Li‡‡ Equal senior authorship

Journal of Thrombosis and Haemostasis24(7), 2522-2531
Natural Language Processing External Validation Clinical Notes Radiology and Pathology Reports Cancer Patients
2026

A deep learning model to dynamically predict cancer-associated thromboembolism in large-scale healthcare systems.

Tianshe He†, Chunlei Zheng†, Jennifer La, Dang Pham, Omid Jafari, Jamie Strampe, Karlynn Dulberger, Jaime Ramos-Cejudo, J. Michael Gaziano, Nhan V. Do, Vipul Chitalia, Katya Ravid, Ang Li‡, Nathanael R. Fillmore‡† Equal first authorship · ‡ Equal senior authorship

npj Digital Medicine
U.S. Veterans and VA Data Electronic Health Records Cancer-Associated Thrombosis Predictive Modeling External Validation
2026

Docetaxel Rechallenge vs Cabazitaxel in Patients With Metastatic Castration-Resistant Prostate Cancer.

Pedro C. Barata†, June K. Corrigan†, Jennifer La, John M. Culnan, Elliot Akama-Garren, Karlynn N. Dulberger, Clark Dumontier, Jason Hansen, John R. Bihn, Rhonda L. Bitting, Mary T. Brophy, Heather H. Cheng, Matthew R. Cooperberg, Nhan V. Do, Tanya Dorff, Antonio Tito Fojo, J. Michael Gaziano, Sergey D. Goryachev, Susan Halabi, Richard L. Hauger, David M. Nanus, Timothy R. Rebbeck, Chong-Xian Pan, Martin W. Schoen, Kaitlin N. Swinnerton, Kenute Myrie, Rachel B. Ramoni, Nathanael R. Fillmore, Channing J. Paller‡, Matthew B. Rettig‡† Equal first authorship · ‡ Equal senior authorship

JAMA Network Open9(1), e2551231
U.S. Veterans and VA Data Retrospective Cohort Study Metastatic Castration-Resistant Prostate Cancer Prostate Cancer Comparative Effectiveness
2026

Magnetic Resonance Imaging or Confirmatory Biopsy for Patients With Prostate Cancer Receiving Active Surveillance.

Matthew R. Cooperberg†, John R. Bihn†, John M. Culnan, Jennifer La, Sergey D. Goryachev, Daniel C. R. Chen, Oleg Soloviev, Grace Lee, June K. Corrigan, Kaitlin N. Swinnerton, Nicholas G. Nickols, Karlynn N. Dulberger, Pedro Barata, Rhonda L. Bitting, Mary T. Brophy, Heather H. Cheng, Hoedt Amanda De, Nhan V. Do, Stephen J. Freedland, Isla P. Garraway, J. Michael Gaziano, Susan Halabi, Richard L. Hauger, Stacy Loeb, David M. Nanus, Timothy R. Rebbeck, Matthew B. Rettig, Chong-Xian Pan, Kenute Myrie, Rachel B. Ramoni, Nathanael R. Fillmore‡, Channing J. Paller‡† Equal first authorship · ‡ Equal senior authorship

JAMA Oncology12(1), 111-113
U.S. Veterans and VA Data Retrospective Cohort Study Electronic Health Records Prostate Cancer Active Surveillance
2026

Rule-based natural language processing to extract clinical trial and research study enrollment history from unstructured notes.

Sergey D. Goryachev†, Julie Tsu-Yu Wu†, Eric Lin†, Daphne R. Friedman, Robert Zwolinski, Rupali Dhond, Danne C. Elbers, Jennifer La, Cenk Yildirim, June K. Corrigan, Daniel C. R. Chen, Mary T. Brophy, Nhan V. Do‡, Nathanael R. Fillmore‡† Equal first authorship · ‡ Equal senior authorship

Health Informatics Journal32(1), 14604582261430614
U.S. Veterans and VA Data Electronic Health Records Natural Language Processing Rule-Based Algorithms Clinical Notes
2025

Dietary tryptophan augments cancer-associated venous thrombogenicity mitigated by indoleamine 2,3-dioxygenase 1 inhibition.

Saran Lotfollahzadeh†, Asha Jose†, Xiaosheng Yang, Tanvi Bathla, Adam Lazowski, Isaac Hoekstra, Kashvi Sethuraman, Sowmya Potluri, Karlynn N. Dulberger, Jennifer La, Nathanael R. Fillmore, Maria Del Carmen Piqueras, Norman Lee, Howard Cabral, Katya Ravid, Vipul C. Chitalia† Equal first authorship

Blood Advances9(19), 4910-4923
Cancer-Associated Thrombosis Colon Cancer Cardio-Oncology Dietary Tryptophan Indoleamine 2,3-Dioxygenase 1 Inhibition
2025

Potentially Inappropriate Medications, Frailty, and Outcomes in Patients With Cancer Managed in a National Health Care System.

Jennifer La, Tammy Hshieh, Anahid Hamparsumian, Robert Zwolinski, Jameson Wood, Mayuri Dharne, J. Michael Gaziano, Mary T. Brophy, Nhan V. Do, Nikhil C. Munshi, Jane A. Driver, Gregory A. Abel, Nathanael R. Fillmore‡, Clark DuMontier‡‡ Equal senior authorship

Journal of the National Comprehensive Cancer Network23(9), 363-370
U.S. Veterans and VA Data Retrospective Cohort Study Electronic Health Records Frailty Overall Survival
2025

Multimorbidity and Its Impact in Older U.S. Veterans Newly Treated for Advanced Non-Small Cell Lung Cancer.

Joseph R. Larsen†, Chunlei Zheng†, Jennifer La, Julie Tsu-Yu Wu, Michael Kelley, J. Michael Gaziano, Mary Brophy, Nhan V. Do, Dae H. Kim, Jane A. Driver, Clark DuMontier‡, Nathanael R. Fillmore‡† Equal first authorship · ‡ Equal senior authorship

Annals of the American Thoracic Society22(4), 598-608
U.S. Veterans and VA Data Retrospective Cohort Study Lung Cancer Overall Survival Geriatric Oncology
2025

Leveraging near-real-time patient and population data to incorporate fluctuating risk of severe COVID-19: development and prospective validation of a personalised risk prediction tool.

Kaitlin Swinnerton†, Nathanael R. Fillmore†, Austin Vo, Jennifer La, Danne Elbers, Mary Brophy, Nhan V. Do, Paul A. Monach‡, Westyn Branch-Elliman‡† Equal first authorship · ‡ Equal senior authorship

eClinicalMedicine81, 103114
U.S. Veterans and VA Data Retrospective Cohort Study COVID-19 Severe COVID-19 Predictive Modeling
2025

External validation of a novel cancer-associated venous thromboembolism risk assessment score in a safety-net hospital.

Karlynn N. Dulberger†, Jennifer La†, Ang Li†, Saran Lotfollahzadeh, Asha Jose, Nhan V. Do, Mary T. Brophy, J. Michael Gaziano, Katya Ravid, Vipul C. Chitalia, Nathanael R. Fillmore† Equal first authorship

Research and Practice in Thrombosis and Haemostasis9(1), 102650
Cancer-Associated Thrombosis External Validation Electronic Health Records Retrospective Cohort Study Cancer Patients
2024

Natural Language Processing Algorithm to Extract Multiple Myeloma Stage From Oncology Notes in the Veterans Affairs Healthcare System.

Sergey D. Goryachev†, Cenk Yildirim†, Clark DuMontier†, Jennifer La†, Mayuri Dharne, J. Michael Gaziano, Mary T. Brophy, Nikhil C. Munshi, Jane A. Driver, Nhan V. Do‡, Nathanael R. Fillmore‡† Equal first authorship · ‡ Equal senior authorship

JCO Clinical Cancer Informatics8, e2300197
U.S. Veterans and VA Data Electronic Health Records Multiple Myeloma Natural Language Processing VA Cancer Registry
2024

Thrombosis risk prediction in lymphoma patients: A multi-institutional, retrospective model development and validation study.

Shengling Ma†, Jennifer La†, Kaitlin N. Swinnerton, Danielle Guffey, Raka Bandyo, Las Pozas Giordana De, Katy Hanzelka, Xiangjun Xiao, Cristhiam M. Rojas-Hernandez, Christopher I. Amos, Vipul Chitalia, Katya Ravid, Kelly W. Merriman, Christopher R. Flowers, Nathanael Fillmore‡, Ang Li‡† Equal first authorship · ‡ Equal senior authorship

American Journal of Hematology99(7), 1230-1239
U.S. Veterans and VA Data Retrospective Cohort Study Cancer-Associated Thrombosis Lymphoma Predictive Modeling
2024

Antidepressant exposure and long-term dementia risk in a nationwide retrospective study on US veterans with midlife major depressive disorder.

Jaime Ramos-Cejudo†, June K. Corrigan†, Chunlei Zheng, Kaitlin N. Swinnerton, Sean R. Jacobson, Jennifer La, Rebecca A. Betensky, Ricardo S. Osorio, Sharon Madanes, Nunzio Pomara, Dan Iosifescu, Mary Brophy, Nhan V. Do‡, Nathanael R. Fillmore‡† Equal first authorship · ‡ Equal senior authorship

Alzheimer's & Dementia20(6), 4106-4114
U.S. Veterans and VA Data Retrospective Cohort Study Alzheimer Disease and Dementia Major Depressive Disorder Antidepressant Therapy
2024

Matching Patients to Accelerate Clinical Trials (MPACT): Enabling Technology for Oncology Clinical Trial Workflow.

Nhan V. Do, Danne C. Elbers, Nathanael R. Fillmore, Samuel Ajjarapu, Steven J. Bergstrom, John Bihn, June K. Corrigan, Rupali Dhond, Svitlana Dipietro, Arkadiy Dolgin, Theodore C. Feldman, Sergey D. Goryachev, Linden B. Huhmann, Jennifer La, Paul A. Marcantonio, Kyle M. McGrath, Stephen J. Miller, Vinh Q. Nguyen, George R. Schneeloch, Feng-Chi Sung, Kaitlin N. Swinnerton, Amelia H. Tarren, Hannah M. Tosi, Danielle Valley, Austin D. Vo, Cenk Yildirim, Chunlei Zheng, Robert Zwolinski, Gisele A. Sarosy, David Loose, Colleen Shannon, Mary T. Brophy

Studies in Health Technology and Informatics310, 1086-1090
U.S. Veterans and VA Data Electronic Health Records Natural Language Processing Clinical Trial Enrollment Patient Screening Workflow
2023

Prostate cancer patient stratification by molecular signatures in the Veterans Precision Oncology Data Commons.

Kyle M. Hernandez†, Aarti Venkat†, Danne C. Elbers†, John R. Bihn, Mary T. Brophy, Nhan V. Do, Jennifer La, Qiong Liu, Andrew Prokhorenkov, Noah Metoki-Shlubsky, Feng-Chi Sung, Channing J. Paller‡, Nathanael R. Fillmore‡, Robert L. Grossman‡† Equal first authorship · ‡ Equal senior authorship

Cold Spring Harbor Molecular Case Studies9(4)
U.S. Veterans and VA Data Retrospective Cohort Study Prostate Cancer Metastatic Castration-Resistant Prostate Cancer Precision Oncology
2023

Maintaining the Utility of Coronavirus Disease 2019 Pandemic Severity Surveillance: Evaluation of Trends in Attributable Deaths and Development and Validation of a Measurement Tool.

Caitlin Trottier†, Jennifer La†, Lucy L. Li†, Majd Alsoubani, Austin D. Vo, Nathanael R. Fillmore, Westyn Branch-Elliman, Shira Doron‡, Paul A. Monach‡† Equal first authorship · ‡ Equal senior authorship

Clinical Infectious Diseases77(9), 1247-1256
COVID-19 U.S. Veterans and VA Data Logistic Regression Model Validation Pandemic Surveillance
2023

More intensive therapy as more effective treatment for frail patients with multiple myeloma [corrected].

Clark DuMontier†, Jennifer La†, John Bihn, June Corrigan, Cenk Yildirim, Mayuri Dharne, Hamza Hassan, Sarvari Yellapragada, Gregory A. Abel, J. Michael Gaziano, Nhan V. Do, Mary Brophy, Dae H. Kim, Nikhil C. Munshi, Nathanael R. Fillmore‡, Jane A. Driver‡† Equal first authorship · ‡ Equal senior authorship

Blood Advances7(20), 6275-6284
U.S. Veterans and VA Data Retrospective Cohort Study Multiple Myeloma Frailty Overall Survival
2023

Machine learning-based natural language processing to extract PD-L1 expression levels from clinical notes.

Eric Lin†, Robert Zwolinski†, Julie Tsu-Yu Wu, Jennifer La, Sergey Goryachev, Linden Huhmann, Cenk Yildrim, David P. Tuck, Danne C. Elbers, Mary T. Brophy, Nhan V. Do‡, Nathanael R. Fillmore‡† Equal first authorship · ‡ Equal senior authorship

Health Informatics Journal29(3), 14604582231198021
U.S. Veterans and VA Data Electronic Health Records Natural Language Processing Machine Learning PD-L1 Expression
2023

Derivation and Validation of a Clinical Risk Assessment Model for Cancer-Associated Thrombosis in Two Unique US Health Care Systems.

Ang Li†, Jennifer La†, Sarah B. May, Danielle Guffey, Costa Wilson L. da, Christopher I. Amos, Raka Bandyo, Emily M. Milner, Karen M. Kurian, Daniel C. R. Chen, Nhan V. Do, Carolina Granada, Nimrah Riaz, Mary T. Brophy, Vipul Chitalia, J. Michael Gaziano, David A. Garcia, Marc Carrier, Christopher R. Flowers, Neil A. Zakai‡, Nathanael R. Fillmore‡† Equal first authorship · ‡ Equal senior authorship

Journal of Clinical Oncology41(16), 2926-2938
Cancer-Associated Thrombosis Predictive Modeling Retrospective Cohort Study External Validation U.S. Veterans and VA Data
2023

Epidemiology of Cancer-Associated Venous Thromboembolism in Patients With Solid and Hematologic Neoplasms in the Veterans Affairs Health Care System.

Kylee L. Martens†, Ang Li†, Jennifer La, Sarah B. May, Kaitlin N. Swinnerton, Hannah Tosi, Danne C. Elbers, Nhan V. Do, Mary T. Brophy, J. Michael Gaziano, Saran Lotfollahzadeh, Vipul Chitalia, Katya Ravid, Nathanael R. Fillmore† Equal first authorship

JAMA Network Open6(6), e2317945
U.S. Veterans and VA Data Retrospective Cohort Study Electronic Health Records Cancer-Associated Thrombosis Health Disparities
2023

Validation of algorithms to select patients with multiple myeloma and patients initiating myeloma treatment in the national Veterans Affairs Healthcare System.

Jennifer La†, Clark DuMontier†, Hamza Hassan, Maya Abdallah, Camille Edwards, Karina Verma, Grace Ferri, Mayuri Dharne, Cenk Yildirim, June Corrigan, J. Michael Gaziano, Nhan V. Do, Mary T. Brophy, Jane A. Driver, Nikhil C. Munshi, Nathanael R. Fillmore† Equal first authorship

Pharmacoepidemiology and Drug Safety32(5), 558-566
U.S. Veterans and VA Data Electronic Health Records Multiple Myeloma VA Cancer Registry Algorithm Validation
2023

Coronavirus disease 2019 (COVID-19) hospitalization metrics that do not account for disease severity underestimate protection provided by severe acute respiratory coronavirus virus 2 (SARS-CoV-2) vaccination and boosting: A retrospective cohort study.

June K. Corrigan†, Jennifer La†, Nathanael R. Fillmore, Nhan V. Do, Mary Brophy, Shira Doron, Paul A. Monach‡, Westyn Branch-Elliman‡† Equal first authorship · ‡ Equal senior authorship

Infection Control and Hospital Epidemiology44(1), 149-151
U.S. Veterans and VA Data Retrospective Cohort Study Electronic Health Records COVID-19 Vaccine Effectiveness
2022

The COVID-19 hospitalization metric in the pre- and postvaccination eras as a measure of pandemic severity: A retrospective, nationwide cohort study.

Nathanael R. Fillmore†, Jennifer La†, Chunlei Zheng, Shira Doron, Nhan V. Do, Paul A. Monach‡, Westyn Branch-Elliman‡† Equal first authorship · ‡ Equal senior authorship

Infection Control and Hospital Epidemiology43(12), 1767-1772
U.S. Veterans and VA Data Retrospective Cohort Study COVID-19 Vaccine Effectiveness Hospitalization Metrics
2022

Increased relative proportions of advanced melanoma among veterans: A comparative analysis with the Surveillance, Epidemiology, and End Results registry.

Michael S. Chang†, Jennifer La†, Nicole Trepanowski, David Cheng, John R. Bihn, Nhan Do, Mary Brophy, Nathanael R. Fillmore‡, Rebecca I. Hartman‡† Equal first authorship · ‡ Equal senior authorship

Journal of the American Academy of Dermatology87(1), 72-79
VA Cancer Registry SEER Database U.S. Veterans and VA Data Cutaneous Melanoma Melanoma Specific Survival
2022

Association of COVID-19 Vaccination With SARS-CoV-2 Infection in Patients With Cancer: A US Nationwide Veterans Affairs Study.

Julie Tsu-Yu Wu†, Jennifer La†, Westyn Branch-Elliman, Linden B. Huhmann, Summer S. Han, Giovanni Parmigiani, David P. Tuck, Mary T. Brophy, Nhan V. Do, Albert Y. Lin‡, Nikhil C. Munshi‡, Nathanael R. Fillmore‡† Equal first authorship · ‡ Equal senior authorship

JAMA Oncology8(2), 281-286
U.S. Veterans and VA Data Retrospective Cohort Study COVID-19 Vaccine Effectiveness Cancer Patients
2021

Evaluating the impact of age on immune checkpoint therapy biomarkers.

Rossin Erbe, Zheyu Wang, Sharon Wu, Joanne Xiu, Neeha Zaidi, Jennifer La, David Tuck, Nathanael Fillmore, Nicolas A. Giraldo, Michael Topper, Stephen Baylin, Marc Lippman, Claudine Isaacs, Reva Basho, Ilya Serebriiskii, Heinz-Josef Lenz, Igor Astsaturov, John Marshall, Josephine Taverna, Jerry Lee, Elizabeth M. Jaffee, Torres Evanthia T. Roussos, Ashani Weeraratna, Hariharan Easwaran, Elana J. Fertig

Cell Reports36(8), 109599
Age Factors Biomarkers Comparative Analysis Genomic Analysis Immune Checkpoint Inhibitors
2021

Defining Multimorbidity and Its Impact in Older United States Veterans Newly Treated for Multiple Myeloma.

Nathanael R. Fillmore†, Clark DuMontier†, Cenk Yildirim, Jennifer La, Mara M. Epstein, David Cheng, Diana Cirstea, Sarvari Yellapragada, Gregory A. Abel, J. Michael Gaziano, Nhan Do, Mary Brophy, Dae H. Kim, Nikhil C. Munshi, Jane A. Driver† Equal first authorship

Journal of the National Cancer Institute113(8), 1084-1093
U.S. Veterans and VA Data Retrospective Cohort Study Multiple Myeloma Overall Survival Geriatric Oncology
2021

Contemporary Analysis of Electronic Frailty Measurement in Older Adults with Multiple Myeloma Treated in the National US Veterans Affairs Healthcare System.

Clark DuMontier†, Nathanael R. Fillmore†, Cenk Yildirim, David Cheng, Jennifer La, Ariela R. Orkaby, Brian Charest, Diana Cirstea, Sarvari Yellapragada, John Michael Gaziano, Nhan Do, Mary T. Brophy, Dae H. Kim, Nikhil C. Munshi, Jane A. Driver† Equal first authorship

Cancers13(12)
U.S. Veterans and VA Data Retrospective Cohort Study Electronic Health Records Multiple Myeloma Frailty
2020

An application to support COVID-19 occupational health and patient tracking at a Veterans Affairs medical center.

Nathanael R. Fillmore†, Danne C. Elbers†, Jennifer La, Theodore C. Feldman, Feng-Chi Sung, Robert B. Hall, Vinh Nguyen, Nicholas Link, Robert Zwolinski, Svitlana Dipietro, Steven J. Miller, Anahit Aleksanyan, Sergey D. Goryachev, Paul Corcoran, Steven J. Bergstrom, Michael A. Parenteau, Robert S. Sprague, David J. Thornton, Jane A. Driver, Judith M. Strymish, Stewart Evans, Benjamin Colonna, Mary T. Brophy, Nhan V. Do† Equal first authorship

Journal of the American Medical Informatics Association27(11), 1716-1720
COVID-19 Occupational Health Patient Tracking Contact Tracing Health Informatics