Nathanael R. Fillmore
Publications / 2026
paper
Journal of the American Academy of Dermatology2026doi:10.1016/j.jaad.2026.02.029

Parkinson's disease and risk of melanoma in United States veterans: A Veterans Affairs Cancer Registry retrospective cohort study.

Jonathan C. Hwang†, Linden B. Huhmann†, David Perez, Daniel Y. Kim, Kaelyn Nannini, Nhan V. Do, John M. Gaziano, Mary T. Brophy, Lee E. Wheless, Nathanael R. Fillmore‡, Rebecca I. Hartman‡

† Equal first authorship · ‡ Equal senior authorship

Summary

Veterans with Parkinson's disease have a nearly twofold higher risk of developing melanoma compared to those without the condition. These findings suggest that patients with Parkinson's disease should be considered a high-risk group and may benefit from increased skin cancer surveillance.

Key result

Veterans with Parkinson's disease had a significantly higher hazard of melanoma compared with those without the disease (adjusted hazard ratio: 1.80; 95% confidence interval, 1.67-1.94; p < 0.001).

Key figure

Key figure from Parkinson's disease and risk of melanoma in United States veterans: A Veterans Affairs Cancer Registry retrospective cohort study.