Nathanael R. Fillmore
Publications / 2020
paper
Blood Advances2020doi:10.1182/bloodadvances.2019001411

Vitamin D deficiency predicts for poor overall survival in white but not African American patients with multiple myeloma.

Sarvari V. Yellapragada†, Nathanael R. Fillmore†, Anna Frolov, Yang Zhou, Pallavi Dev, Hassan Yameen, Chizoba Ifeorah, Nhan V. Do, Mary T. Brophy, Nikhil C. Munshi

† Equal first authorship

Summary

Vitamin D deficiency is associated with lower overall survival rates in white patients with multiple myeloma. This predictive relationship was not observed in African American patients, suggesting that the impact of vitamin D levels on prognosis may vary by racial group.

Key result

Vitamin D deficiency predicts poor overall survival in white patients with multiple myeloma, whereas no such association exists for African American patients.

Abstract

Vitamin D deficiency is a predictor for poor overall survival in patients with multiple myeloma, even after adjusting for age and stage. This difference is only observed in white patients, not African Americans, even under a lower threshold for deficiency.

Key figure

Key figure from Vitamin D deficiency predicts for poor overall survival in white but not African American patients with multiple myeloma.