Fine-Gray Models

Fillmore has employed Fine-Gray models to analyze the cumulative incidence of competing risks, particularly in the context of cardiovascular and thromboembolic events among patients with cancer. His work utilizes subdistribution hazard ratios to determine how variables such as circulating tumor DNA mutations, allostatic load, and malignancy type independently influence the risk of venous and arterial thrombosis. These analyses allow for more accurate risk stratification and the development of predictive models that account for the high mortality rates inherent in oncology populations.