Geriatric Oncology

Fillmore has examined the impact of frailty and multimorbidity on clinical outcomes for older adults with malignancies, specifically multiple myeloma and non-small cell lung cancer. His research demonstrates that specific patterns of multisystem impairment and the use of potentially inappropriate medications are more predictive of mortality and unplanned hospitalization than chronological age or the total number of comorbidities. Additionally, he has evaluated the sensitivity of existing frailty assessment tools, highlighting the necessity for scalable, electronic indices to better identify vulnerable patients and guide individualized treatment strategies.