Multimorbidity

Fillmore has investigated the impact of multimorbidity on clinical outcomes in older adults with cancer, demonstrating that specific patterns of co-occurring illnesses are more predictive of mortality and unplanned hospitalization than the total number of comorbidities. His research indicates that multisystem impairment significantly increases the risk of death in patients with advanced non-small cell lung cancer and multiple myeloma. Additionally, he has examined how the use of potentially inappropriate medications and the limitations of current frailty scoring systems further complicate the management of these complex patient populations.