Taxane Therapy
Research led by Fillmore has examined optimal sequencing strategies for taxane therapy in patients with metastatic castration-resistant prostate cancer. His work demonstrates that docetaxel rechallenge provides a significant survival advantage over cabazitaxel for patients who did not progress during their initial docetaxel course. These findings suggest that repeating a previously effective taxane may be a superior second-line therapeutic option for this specific patient population.
Publications (1)
2026
Pedro C. Barata†, June K. Corrigan†, Jennifer La, John M. Culnan, Elliot Akama-Garren, Karlynn N. Dulberger, Clark Dumontier, Jason Hansen, John R. Bihn, Rhonda L. Bitting, Mary T. Brophy, Heather H. Cheng, Matthew R. Cooperberg, Nhan V. Do, Tanya Dorff, Antonio Tito Fojo, J. Michael Gaziano, Sergey D. Goryachev, Susan Halabi, Richard L. Hauger, David M. Nanus, Timothy R. Rebbeck, Chong-Xian Pan, Martin W. Schoen, Kaitlin N. Swinnerton, Kenute Myrie, Rachel B. Ramoni, Nathanael R. Fillmore, Channing J. Paller‡, Matthew B. Rettig‡
JAMA Network Open9(1), e2551231